Flow-layer physical design for microchips based on monolithic membrane valves

Jeffrey McDaniel, Brian Crites, Philip Brisk, and William H. Grover. IEEE Design and Test 32 (6), 51-59 (2015). PDF

This article introduces a software toolchain for physical design and layout for the flow layer of microfluidic LoCs based on integrated microvalve technology. A case study shows that it can automatically produce layouts for the Mars Organic Analyzer LoC to detect biomolecules in soil on Mars.